Difference between revisions of "YqfL"

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Revision as of 08:39, 20 April 2012

  • Description: Modulator of CcpN activity

Gene name yqfL
Synonyms
Essential no
Product modulator of CcpN activity
Function inhibits CcpN activity
MW, pI 30,4 kDa, 5.78
Gene length, protein length 810 bp, 270 amino acids
Immediate neighbours yqxD, ccpN
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YqfL context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YqfL expression.png

























Categories containing this gene/protein

carbon core metabolism, transcription factors and their control

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU25240

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry:[2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: negative effector of CcpN activity PubMed
  • Protein family: pyruvate, phosphate dikinase regulatory protein family (according to Swiss-Prot) pyruvate, phosphate dikinase regulatory protein family
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains: nucleotide binding domain (ATP) (151–158)
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation: constitutive PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • Antibody:

Labs working on this gene/protein

Stephane Aymerich, Microbiology and Molecular Genetics, INRA Paris-Grignon, France


Your additional remarks

References

Pascale Servant, Dominique Le Coq, Stéphane Aymerich
CcpN (YqzB), a novel regulator for CcpA-independent catabolite repression of Bacillus subtilis gluconeogenic genes.
Mol Microbiol: 2005, 55(5);1435-51
[PubMed:15720552] [WorldCat.org] [DOI] (P p)