Difference between revisions of "RsbV"

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Revision as of 14:46, 18 April 2012

  • Description: anti-anti-SigB, antagonist of RsbW

Gene name rsbV
Synonyms
Essential no
Product anti-anti-SigB
Function control of SigB activity
Interactions involving this protein in SubtInteract: RsbV
Metabolic function and regulation of this protein in SubtiPathways:
Stress
MW, pI 11 kDa, 4.698
Gene length, protein length 327 bp, 109 aa
Immediate neighbours rsbU, rsbW
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
RsbV context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
RsbV expression.png




























Categories containing this gene/protein

sigma factors and their control, general stress proteins (controlled by SigB), phosphoproteins

This gene is a member of the following regulons

CcpA regulon, SigB regulon

The gene

Basic information

  • Locus tag: BSU04710

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: STAS domain (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 1VC1 (homolog from Thermotoga maritima)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
    • CcpA: transcription repression PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Locke JC, Young JW, Fontes M, Hernández Jiménez MJ, Elowitz MB  
Stochastic pulse regulation in bacterial stress response. 
Science. 2011 334:366-369. 
PubMed:21979936