Difference between revisions of "PrsA"
m (Reverted edits by 134.76.70.252 (talk) to last revision by Jstuelk) |
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* '''Modification:''' | * '''Modification:''' | ||
| + | ** PrsA is a lipoprotein with a N-acetyl-S-diacyl-glyceryl-cysteine structure {{PubMed|22303020}} | ||
* '''Cofactor(s):''' | * '''Cofactor(s):''' | ||
| Line 86: | Line 87: | ||
** dimeric or oligomeric protein {{PubMed|20487272}} | ** dimeric or oligomeric protein {{PubMed|20487272}} | ||
| − | * '''[[Localization]]:''' membrane associated {{PubMed| | + | * '''[[Localization]]:''' |
| + | ** membrane associated (lipoprotein) {{PubMed|22303020}} | ||
| + | ** distinct spots organized in a helical pattern along the cell membrane {{PubMed|20487272}} | ||
=== Database entries === | === Database entries === | ||
| Line 132: | Line 135: | ||
=References= | =References= | ||
| − | <pubmed>12634326,14976191,11807061,10096076,18763711, 10871614 20487272 </pubmed> | + | <pubmed>12634326,14976191,11807061,10096076,18763711, 10871614 20487272 22303020</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 17:16, 12 February 2012
- Description: post-translocational folding of exported proteins (post-translocation molecular chaperone)
| Gene name | prsA |
| Synonyms | |
| Essential | yes PubMed |
| Product | post-translocation molecular chaperone |
| Function | protein folding |
| Interactions involving this protein in SubtInteract: PrsA | |
| Metabolic function and regulation of this protein in SubtiPathways: Protein secretion | |
| MW, pI | 32 kDa, 9.122 |
| Gene length, protein length | 876 bp, 292 aa |
| Immediate neighbours | yhaL, sscA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
protein secretion, essential genes, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU09950
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: catalyses the post-translocational folding of exported proteins PubMed, required for folding of penicillin-binding proteins (PbpA, PbpB, PbpC, PbpD) PubMed
- Protein family: PpiC domain (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- PrsA is a lipoprotein with a N-acetyl-S-diacyl-glyceryl-cysteine structure PubMed
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- dimeric or oligomeric protein PubMed
Database entries
- Structure: 1ZK6
- UniProt: P24327
- KEGG entry: [2]
- E.C. number: 5.2.1.8
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
