NdoAI

• Description: antitoxin, inhibits EndoA
  
  

Gene name	ndoAI
Synonyms	ydcD
Essential	no
Product	antitoxin
Function	inhibition of NdoA
Interactions involving this protein in SubtInteract: NdoAI
MW, pI	10 kDa, 6.138
Gene length, protein length	279 bp, 93 aa
Immediate neighbours	alr, ndoA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

toxins, antitoxins and immunity against toxins

The gene

Basic information

• Locus tag: BSU04650

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: mazE/ndoAI family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • NdoAI-EndoA PubMed

• Localization:

Database entries

• Structure:

• UniProt: P96621

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: ndoAI-ndoA PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Shivangi Agarwal, Shivani Agarwal, Rakesh Bhatnagar
Identification and characterization of a novel toxin-antitoxin module from Bacillus anthracis.
FEBS Lett: 2007, 581(9);1727-34
[PubMed:17416361] [WorldCat.org] [DOI] (P p)

Olivier Pellegrini, Nathalie Mathy, Arhonda Gogos, Lawrence Shapiro, Ciarán Condon
The Bacillus subtilis ydcDE operon encodes an endoribonuclease of the MazF/PemK family and its inhibitor.
Mol Microbiol: 2005, 56(5);1139-48
[PubMed:15882409] [WorldCat.org] [DOI] (P p)