FadG

• Description: fatty acid degradation
  
  

Gene name	fadG
Synonyms	ykuG
Essential	no
Product	unknown
Function	fatty acid degradation
Metabolic function and regulation of this protein in SubtiPathways: Fatty acid degradation
MW, pI	64 kDa, 8.556
Gene length, protein length	1728 bp, 576 aa
Immediate neighbours	fadH, ykzU
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

utilization of lipids

This gene is a member of the following regulons

FadR regulon

The gene

Basic information

• Locus tag: BSU14071

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: fadG family (according to Swiss-Prot)

• Paralogous protein(s): YbfG

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: C0H407

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: fadH-fadG PubMed

• Sigma factor:

• Regulation:
  • induced in the presence of long-chain fatty acids (FadR) PubMed

• Regulatory mechanism:
  • FadR: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Hiroshi Matsuoka, Kazutake Hirooka, Yasutaro Fujita
Organization and function of the YsiA regulon of Bacillus subtilis involved in fatty acid degradation.
J Biol Chem: 2007, 282(8);5180-94
[PubMed:17189250] [WorldCat.org] [DOI] (P p)