Rnr

• Description: RNase R
  
  

Gene name	rnr
Synonyms	yvaJ
Essential	no
Product	exoribonuclease RNase R (EC 3.1.-.-)
Function	nonspecific degradation of rRNA
MW, pI	88 kDa, 5.703
Gene length, protein length	2337 bp, 779 aa
Immediate neighbours	smpB, yvaK
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

biosynthesis/ acquisition of nucleotides, Rnases

This gene is a member of the following regulons

SigB regulon

The gene

Basic information

• Locus tag: BSU33610

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: 3'-5'-exoribonuclease

• Protein family: ribonuclease II (RNB) family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O32231

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:
  • secG-yvaK-rnr-smpB-ssrA PubMed
  • yvaK-rnr-smpB-ssrA PubMed

• Sigma factor:
  • yvaK: SigB PubMed

• Regulation:
  • yvaK: induced by stress (SigB) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

David Bechhofer, Mount Sinai School, New York, USA Homepage