Difference between revisions of "LmrA"
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* '''Effectors of protein activity:''' flavonoids such as quercetin serve as inducers, binding results in release from DNA {{PubMed|17483215}} | * '''Effectors of protein activity:''' flavonoids such as quercetin serve as inducers, binding results in release from DNA {{PubMed|17483215}} | ||
− | * '''Interactions:''' | + | * '''[[SubtInteract|Interactions]]:''' |
− | * '''Localization:''' | + | * '''[[Localization]]:''' |
=== Database entries === | === Database entries === | ||
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* '''Additional information:''' | * '''Additional information:''' | ||
+ | ** the mRNA is substantially stabilized upon depletion of [[Rny|RNase Y]] {{PubMed|21815947}} | ||
=Biological materials = | =Biological materials = | ||
Line 126: | Line 127: | ||
=References= | =References= | ||
− | + | <big>''Lehnik-Habrink M, Schaffer M, Mäder U, Diethmaier C, Herzberg C, Stülke J'' </big> | |
+ | <big>'''RNA processing in ''Bacillus subtilis'': identification of targets of the essential RNase Y.''' </big> | ||
+ | <big>Mol Microbiol. 2011 81(6): 1459-1473. </big> | ||
+ | [http://www.ncbi.nlm.nih.gov/pubmed/21815947 PubMed:21815947] | ||
<pubmed>15317768,17483215,12499232 , </pubmed> | <pubmed>15317768,17483215,12499232 , </pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] |
Revision as of 19:36, 19 November 2011
Gene name | lmrA |
Synonyms | lin-2, yccB |
Essential | no |
Product | transcriptional regulator |
Function | regulation of lincomycin resistance |
MW, pI | 20 kDa, 5.033 |
Gene length, protein length | 564 bp, 188 aa |
Immediate neighbours | lmrB, ansZ |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
transcription factors and their control, resistance against toxins/ antibiotics
This gene is a member of the following regulons
The LmrA regulon:
The gene
Basic information
- Locus tag: BSU02680
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s): QdoR
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity: flavonoids such as quercetin serve as inducers, binding results in release from DNA PubMed
Database entries
- Structure:
- UniProt: O34619
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Lehnik-Habrink M, Schaffer M, Mäder U, Diethmaier C, Herzberg C, Stülke J RNA processing in Bacillus subtilis: identification of targets of the essential RNase Y. Mol Microbiol. 2011 81(6): 1459-1473. PubMed:21815947