Difference between revisions of "DegS"
(→Extended information on the protein) |
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* '''Domains:''' | * '''Domains:''' | ||
| − | |||
** aa 12 ... 170: unknown DegS domain | ** aa 12 ... 170: unknown DegS domain | ||
** aa 180 ... 248: HisKA_3 domain (autophosphorylation) | ** aa 180 ... 248: HisKA_3 domain (autophosphorylation) | ||
| Line 86: | Line 85: | ||
* '''Cofactor(s):''' | * '''Cofactor(s):''' | ||
| − | * '''Effectors of protein activity:''' [[DegQ]] (stimulation of autophosphorylation) | + | * '''Effectors of protein activity:''' [[DegQ]] (stimulation of autophosphorylation) {{PubMed|21965392}} |
* '''[[SubtInteract|Interactions]]:''' | * '''[[SubtInteract|Interactions]]:''' | ||
| − | ** [[DegS]]-[[DegU]] | + | ** [[DegS]]-[[DegU]] |
| + | ** [[DegS]]-[[DegQ]] {{PubMed|21965392}} | ||
* '''[[Localization]]:''' Cytoplasm (Homogeneous) [http://www.ncbi.nlm.nih.gov/sites/entrez/16479537 PubMed] | * '''[[Localization]]:''' Cytoplasm (Homogeneous) [http://www.ncbi.nlm.nih.gov/sites/entrez/16479537 PubMed] | ||
| Line 138: | Line 138: | ||
=References= | =References= | ||
| − | + | '''Additional publications:''' {{PubMed|21965392}} | |
<pubmed>17850253,12471443,14563871,1459944,1901568,10094672,1688843 ,16479537, 17218307 21304896 </pubmed> | <pubmed>17850253,12471443,14563871,1459944,1901568,10094672,1688843 ,16479537, 17218307 21304896 </pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 09:20, 6 October 2011
- Description: two-component sensor kinase for exoenzyme and competence regulation
| Gene name | degS |
| Synonyms | sacU |
| Essential | no |
| Product | two-component sensor kinase |
| Function | regulation of degradative enzyme and genetic competence |
| Interactions involving this protein in SubtInteract: DegS | |
| MW, pI | 44 kDa, 5.988 |
| Gene length, protein length | 1155 bp, 385 aa |
| Immediate neighbours | degU, yvyE |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
protein modification, transcription factors and their control, phosphoproteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU35500
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: autophosphorylation, autodephosphorylation, phosphorylation of DegU on Asp-56 PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- aa 12 ... 170: unknown DegS domain
- aa 180 ... 248: HisKA_3 domain (autophosphorylation)
- aa 289 ... 384: HATPase_c
- Modification:
- Cofactor(s):
- Localization: Cytoplasm (Homogeneous) PubMed
Database entries
- Structure:
- UniProt: P13799
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Tarek Msadek, Institut Pasteur, Paris, France
Your additional remarks
References
Additional publications: PubMed
