Difference between revisions of "RNA polymerase"
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* [[NusA]]: essential elongation factor | * [[NusA]]: essential elongation factor | ||
* [[GreA]]: resolve promoter proximal pausing of RNA polymerase {{PubMed|21515770}} | * [[GreA]]: resolve promoter proximal pausing of RNA polymerase {{PubMed|21515770}} | ||
| − | * [[CshA]]: [[DEAD-box RNA helicase]] {{PubMed|21710567}} | + | * [[CshA]]: [[DEAD-box RNA helicases|DEAD-box RNA helicase]] {{PubMed|21710567}} |
===Temporary interaction partners=== | ===Temporary interaction partners=== | ||
Revision as of 08:50, 2 July 2011
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Contents
The enzyme responsible for transcription
Components of the RNA polymerase
Core subunits
Sigma factors
- In addition to the housekeeping sigma factor, SigA, there are several other sigma factors with different promoter recognition specifiity that are active under specific conditions (such as stress or sporulation)
Small accessory subunits
Other interaction partners
- NusA: essential elongation factor
- GreA: resolve promoter proximal pausing of RNA polymerase PubMed
- CshA: DEAD-box RNA helicase PubMed
Temporary interaction partners
- Spx: transcription regulator, interacts with RpoA
- MgsR: transcription regulator orthologous to Spx, interacts with RpoA
- Additional interaction partners of the RNA polymerase (no specific subunit specified)
Back to protein-protein interactions
References
Reviews
Finn Werner, Dina Grohmann
Evolution of multisubunit RNA polymerases in the three domains of life.
Nat Rev Microbiol: 2011, 9(2);85-98
[PubMed:21233849]
[WorldCat.org]
[DOI]
(I p)
Vladimir Svetlov, Evgeny Nudler
Macromolecular micromovements: how RNA polymerase translocates.
Curr Opin Struct Biol: 2009, 19(6);701-7
[PubMed:19889534]
[WorldCat.org]
[DOI]
(I p)
Evgeny Nudler
RNA polymerase active center: the molecular engine of transcription.
Annu Rev Biochem: 2009, 78;335-61
[PubMed:19489723]
[WorldCat.org]
[DOI]
(I p)
P J Lewis, G P Doherty, J Clarke
Transcription factor dynamics.
Microbiology (Reading): 2008, 154(Pt 7);1837-1844
[PubMed:18599813]
[WorldCat.org]
[DOI]
(P p)
Kristina M Herbert, William J Greenleaf, Steven M Block
Single-molecule studies of RNA polymerase: motoring along.
Annu Rev Biochem: 2008, 77;149-76
[PubMed:18410247]
[WorldCat.org]
[DOI]
(P p)
Sergei Borukhov, Evgeny Nudler
RNA polymerase: the vehicle of transcription.
Trends Microbiol: 2008, 16(3);126-34
[PubMed:18280161]
[WorldCat.org]
[DOI]
(P p)
W G Haldenwang
The sigma factors of Bacillus subtilis.
Microbiol Rev: 1995, 59(1);1-30
[PubMed:7708009]
[WorldCat.org]
[DOI]
(P p)
The structure of RNA polymerase
Important original publications: PubMed
Yoko Kusuya, Ken Kurokawa, Shu Ishikawa, Naotake Ogasawara, Taku Oshima
Transcription factor GreA contributes to resolving promoter-proximal pausing of RNA polymerase in Bacillus subtilis cells.
J Bacteriol: 2011, 193(12);3090-9
[PubMed:21515770]
[WorldCat.org]
[DOI]
(I p)
Houra Merrikh, Cristina Machón, William H Grainger, Alan D Grossman, Panos Soultanas
Co-directional replication-transcription conflicts lead to replication restart.
Nature: 2011, 470(7335);554-7
[PubMed:21350489]
[WorldCat.org]
[DOI]
(I p)
