Difference between revisions of "LiaR"
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* '''Regulation:''' | * '''Regulation:''' | ||
** ''[[liaI]]'': induced by bacitracin ([[LiaR]]) {{PubMed|16816187}} | ** ''[[liaI]]'': induced by bacitracin ([[LiaR]]) {{PubMed|16816187}} | ||
| − | ** ''[[liaI]]'':repressed during logarithmic growth ([[AbrB]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/15101989,17660417 PubMed] | + | ** ''[[liaI]]'':repressed during logarithmic growth ([[AbrB]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/15101989,17660417 PubMed], indirect regulation by [[AbrB]] {{PubMed|20817675}} |
** ''[[liaG]]'': constitutive | ** ''[[liaG]]'': constitutive | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
** [[LiaR]]: transcription activation {{PubMed|16816187}} | ** [[LiaR]]: transcription activation {{PubMed|16816187}} | ||
| − | |||
* '''Additional information:''' | * '''Additional information:''' | ||
Revision as of 17:17, 30 May 2011
- Description: two-component response regulator, regulation of the liaI-liaH-liaG-liaF-liaS-liaR operon in response to bacitracin
| Gene name | liaR |
| Synonyms | yvqC |
| Essential | no |
| Product | two-component response regulator |
| Function | regulation of the liaI-liaH-liaG-liaF-liaS-liaR operon in response to bacitracin |
| MW, pI | 22 kDa, 4.956 |
| Gene length, protein length | 633 bp, 211 aa |
| Immediate neighbours | gerAC, liaS |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
transcription factors and their control, resistance against oxidative and electrophile stress, resistance against toxins/ antibiotics, phosphoproteins
This gene is a member of the following regulons
The LiaR regulon
The gene
Basic information
- Locus tag: BSU33080
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: regulation of the liaI-liaH-liaG-liaF-liaS-liaR operon in response to bacitracin
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: phosphorylation on a Asp residue by LiaS
- Cofactor(s):
- Effectors of protein activity:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: O32197
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
John Helmann, Cornell University, USA Homepage
Your additional remarks
References
