Difference between revisions of "QueG"
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|style="background:#ABCDEF;" align="center"| '''Product''' || epoxyqueuosine reductase | |style="background:#ABCDEF;" align="center"| '''Product''' || epoxyqueuosine reductase | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || synthesis of queuosine, [[tRNA modification]] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 48 kDa, 7.352 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 48 kDa, 7.352 | ||
| Line 52: | Line 52: | ||
=== Additional information=== | === Additional information=== | ||
| − | |||
| − | |||
| Line 60: | Line 58: | ||
=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' conversion of epoxyqueuosine to queuosine {{PubMed|21502530}} |
* '''Protein family:''' | * '''Protein family:''' | ||
| Line 74: | Line 72: | ||
* '''Modification:''' | * '''Modification:''' | ||
| − | * '''Cofactor(s):''' | + | * '''Cofactor(s):''' cobalamin, iron-sulfur cluster {{PubMed|21502530}} |
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
Revision as of 07:53, 20 April 2011
- Description: epoxyqueuosine reductase
| Gene name | yhbA |
| Synonyms | ygaP |
| Essential | no |
| Product | epoxyqueuosine reductase |
| Function | synthesis of queuosine, tRNA modification |
| MW, pI | 48 kDa, 7.352 |
| Gene length, protein length | 1305 bp, 435 aa |
| Immediate neighbours | yhzB, yhbB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU08910
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: conversion of epoxyqueuosine to queuosine PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s): cobalamin, iron-sulfur cluster PubMed
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P97030
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Zachary D Miles, Reid M McCarty, Gabriella Molnar, Vahe Bandarian
Discovery of epoxyqueuosine (oQ) reductase reveals parallels between halorespiration and tRNA modification.
Proc Natl Acad Sci U S A: 2011, 108(18);7368-72
[PubMed:21502530]
[WorldCat.org]
[DOI]
(I p)
