Difference between revisions of "RNA polymerase"
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===Other temporary components=== | ===Other temporary components=== | ||
* [[NusA]]: essential elongation factor | * [[NusA]]: essential elongation factor | ||
| + | * [[Spx]]: transcription regulator, interacts with [[RpoA]] | ||
| + | * [[MgsR]]: transcription regulator orthologous to [[Spx]], interacts with [[RpoA]] | ||
==Back to [[protein-protein interactions]]== | ==Back to [[protein-protein interactions]]== | ||
Revision as of 14:11, 8 April 2011
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Contents
The enzyme responsible for transcription
Components of the RNA polymerase
Core subunits
Sigma factors
- In addition to the housekeeping sigma factor, SigA, there are several other sigma factors with different promoter recognition specifiity that are active under specific conditions (such as stress or sporulation)
Small accessory subunits
Other temporary components
- NusA: essential elongation factor
- Spx: transcription regulator, interacts with RpoA
- MgsR: transcription regulator orthologous to Spx, interacts with RpoA
Back to protein-protein interactions
References
Reviews
Finn Werner, Dina Grohmann
Evolution of multisubunit RNA polymerases in the three domains of life.
Nat Rev Microbiol: 2011, 9(2);85-98
[PubMed:21233849]
[WorldCat.org]
[DOI]
(I p)
Vladimir Svetlov, Evgeny Nudler
Macromolecular micromovements: how RNA polymerase translocates.
Curr Opin Struct Biol: 2009, 19(6);701-7
[PubMed:19889534]
[WorldCat.org]
[DOI]
(I p)
Evgeny Nudler
RNA polymerase active center: the molecular engine of transcription.
Annu Rev Biochem: 2009, 78;335-61
[PubMed:19489723]
[WorldCat.org]
[DOI]
(I p)
P J Lewis, G P Doherty, J Clarke
Transcription factor dynamics.
Microbiology (Reading): 2008, 154(Pt 7);1837-1844
[PubMed:18599813]
[WorldCat.org]
[DOI]
(P p)
Kristina M Herbert, William J Greenleaf, Steven M Block
Single-molecule studies of RNA polymerase: motoring along.
Annu Rev Biochem: 2008, 77;149-76
[PubMed:18410247]
[WorldCat.org]
[DOI]
(P p)
Sergei Borukhov, Evgeny Nudler
RNA polymerase: the vehicle of transcription.
Trends Microbiol: 2008, 16(3);126-34
[PubMed:18280161]
[WorldCat.org]
[DOI]
(P p)
W G Haldenwang
The sigma factors of Bacillus subtilis.
Microbiol Rev: 1995, 59(1);1-30
[PubMed:7708009]
[WorldCat.org]
[DOI]
(P p)
The structure of RNA polymerase
Important original publications: PubMed
Houra Merrikh, Cristina Machón, William H Grainger, Alan D Grossman, Panos Soultanas
Co-directional replication-transcription conflicts lead to replication restart.
Nature: 2011, 470(7335);554-7
[PubMed:21350489]
[WorldCat.org]
[DOI]
(I p)
