KtrA

• Description: high affinity potassium transporter KtrA-KtrB, peripheric membrane component (proton symport)
  
  

Gene name	ktrA
Synonyms	yuaA
Essential	no
Product	high affinity potassium transporter KtrA-KtrB, peripheric membrane component (proton symport)
Function	potassium uptake
Metabolic function and regulation of this protein in SubtiPathways: metal ion homeostasis
Metabolic function and regulation of this protein in SubtiPathways: Stress
MW, pI	24 kDa, 5.981
Gene length, protein length	666 bp, 222 aa
Immediate neighbours	yuaB, ktrB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

transporters/ other, metal ion homeostasis (K, Na, Ca, Mg), coping with hyper-osmotic stress, membrane proteins

This gene is a member of the following regulons

YdaO riboswitch

The gene

Basic information

• Locus tag: BSU31090

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s): KtrC

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: KtrA-KtrB PubMed

• Localization: cell membrane (according to Swiss-Prot), peripheral membrane protein PubMed

Database entries

• Structure: 1LSU (complex with NADH), 2HMW ( complex with ATP)

• UniProt: O32080

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: ktrA-ktrB PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:
  • expression is controlled via termination antitermination by the ydaO riboswitch PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Erhard Bremer, University of Marburg, Germany homepage