Difference between revisions of "FrlB"

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(References)
(Expression and regulation)
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=Expression and regulation=
 
=Expression and regulation=
* '''Operon:''' ''[[yurR]]-[[yurQ]]-[[yurP]]-[[yurO]]-[[yurN]]-[[yurM]]-[[yurL]]'' {{PubMed|12823818}}
+
* '''Operon:'''  
 +
** ''[[yurR]]-[[yurQ]]-[[frlB]]-[[frlO]]-[[frlN]]-[[frlM]]-[[frlD]]'' {{PubMed|12823818}}
 +
** ''[[frlB]]-[[frlO]]-[[frlN]]-[[frlM]]-[[frlD]]'' {{PubMed|21347729}}
  
 
* '''[[Sigma factor]]:'''  
 
* '''[[Sigma factor]]:'''  
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
** repressed during growth in the presence of branched chain amino acids ([[CodY]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12618455 PubMed]
+
**'' [[yurR]]'': repressed during growth in the presence of branched chain amino acids ([[CodY]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12618455 PubMed]
 +
** ''[[frlB]]'': induced in the presence of fructosamine ([[FrlR]]) {{PubMed|21347729}}
  
 
* '''Regulatory mechanism:'''   
 
* '''Regulatory mechanism:'''   
 
** [[CodY]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/12618455 PubMed1], [http://www.ncbi.nlm.nih.gov/sites/entrez/18083814 PubMed2]
 
** [[CodY]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/12618455 PubMed1], [http://www.ncbi.nlm.nih.gov/sites/entrez/18083814 PubMed2]
 +
** [[FrlR]]: transcription repression {{PubMed|21347729}}
  
 
* '''Additional information:'''
 
* '''Additional information:'''

Revision as of 17:47, 27 February 2011

  • Description: fructosamine 6-phosphate glycosidase

Gene name frlB
Synonyms yurP
Essential no
Product fructosamine 6-phosphate glycosidase
Function metabolism of sugar amines
Metabolic function and regulation of this protein in SubtiPathways:
Alternative nitrogen sources
MW, pI 36 kDa, 5.442
Gene length, protein length 984 bp, 328 aa
Immediate neighbours frlO, yurQ
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YurP context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

utilization of specific carbon sources, utilization of nitrogen sources other than amino acids, membrane proteins

This gene is a member of the following regulons

CodY regulon

The gene

Basic information

  • Locus tag: BSU32610

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: membrane associated PubMed

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • yurR: repressed during growth in the presence of branched chain amino acids (CodY) PubMed
    • frlB: induced in the presence of fructosamine (FrlR) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References