Difference between revisions of "ProI"
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* '''Operon:''' ''proI'' (according to [http://dbtbs.hgc.jp/COG/prom/proI.html DBTBS]) | * '''Operon:''' ''proI'' (according to [http://dbtbs.hgc.jp/COG/prom/proI.html DBTBS]) | ||
| − | * '''[[Sigma factor]]:''' | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|21233158}} |
* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** induced by proline limitation ([[T-box]]) {{PubMed| | + | ** induced by proline limitation ([[T-box]]) {{PubMed|21233158}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | ** [[T-box]]: [[RNA switch]], transcriptional antitermination {{PubMed| | + | ** [[T-box]]: [[RNA switch]], transcriptional antitermination {{PubMed|21233158}} |
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 130: | Line 130: | ||
=References= | =References= | ||
| − | <pubmed>19258532,,11418582, </pubmed> | + | <pubmed>19258532,21233158,11418582, </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 10:10, 17 January 2011
- Description: pyrroline-5-carboxylate reductase
| Gene name | proI |
| Synonyms | yqjO |
| Essential | no |
| Product | pyrroline-5-carboxylate reductase |
| Function | biosynthesis of proline |
| Metabolic function and regulation of this protein in SubtiPathways: Pro, Stress | |
| MW, pI | 30 kDa, 6.702 |
| Gene length, protein length | 834 bp, 278 aa |
| Immediate neighbours | yqjP, yqjN |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
biosynthesis/ acquisition of amino acids
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU23800
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: L-proline + NAD(P)+ = 1-pyrroline-5-carboxylate + NAD(P)H (according to Swiss-Prot)
- Protein family: pyrroline-5-carboxylate reductase family (according to Swiss-Prot)
- Paralogous protein(s): ProH
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P54552
- KEGG entry: [3]
- E.C. number: 1.5.1.2
Additional information
Expression and regulation
- Operon: proI (according to DBTBS)
- Regulatory mechanism:
- T-box: RNA switch, transcriptional antitermination PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
