Difference between revisions of "PbpB"
| Line 87: | Line 87: | ||
** folding requires [[PrsA]] {{PubMed|20487272}} | ** folding requires [[PrsA]] {{PubMed|20487272}} | ||
** [[PbpB]]-[[DivIB]]-([[FtsL]]-[[DivIC]])2 {{PubMed|20870765}}, as part of the [[divisome]] | ** [[PbpB]]-[[DivIB]]-([[FtsL]]-[[DivIC]])2 {{PubMed|20870765}}, as part of the [[divisome]] | ||
| + | ** [[WalK]]-[[PbpB]] {{PubMed|21219466}} | ||
* '''Localization:''' cell membrane {{PubMed|20870765}}, extracellular (signal peptide) [http://www.ncbi.nlm.nih.gov/pubmed/18957862 PubMed], localizes to the sporulation septum during sporulation [http://www.ncbi.nlm.nih.gov/sites/entrez/15758244 PubMed] | * '''Localization:''' cell membrane {{PubMed|20870765}}, extracellular (signal peptide) [http://www.ncbi.nlm.nih.gov/pubmed/18957862 PubMed], localizes to the sporulation septum during sporulation [http://www.ncbi.nlm.nih.gov/sites/entrez/15758244 PubMed] | ||
| Line 137: | Line 138: | ||
=References= | =References= | ||
| − | <pubmed>8636036,14731276,8244929,20487272,10652091, 19429628, 18957862 20870765 </pubmed> | + | <pubmed>8636036,14731276,8244929,20487272,10652091, 19429628, 18957862 20870765 21219466</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 10:12, 12 January 2011
- Description: penicillin-binding protein 2B
| Gene name | pbpB |
| Synonyms | |
| Essential | yes PubMed |
| Product | penicillin-binding protein 2B |
| Function | septation |
| MW, pI | 79 kDa, 9.234 |
| Gene length, protein length | 2148 bp, 716 aa |
| Immediate neighbours | ftsL, spoVD |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
cell wall synthesis, essential genes, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU15160
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: transpeptidase family (according to Swiss-Prot)
- Paralogous protein(s): SpoVD
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane PubMed, extracellular (signal peptide) PubMed, localizes to the sporulation septum during sporulation PubMed
Database entries
- Structure:
- UniProt: Q07868
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- constitutively expressed PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system: B. pertussis adenylate cyclase-based bacterial two hybrid system (BACTH), available in Jeff Errington lab
- Antibody:
Labs working on this gene/protein
Jeff Errington, Newcastle University, UK homepage
Your additional remarks
References
