Difference between revisions of "CtpB"
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| + | = [[Categories]] containing this gene/protein = | ||
| + | {{SubtiWiki category|[[proteolysis]]}}, | ||
| + | {{SubtiWiki category|[[sigma factors and their control]]}}, | ||
| + | {{SubtiWiki category|[[sporulation proteins]]}} | ||
| + | |||
| + | = This gene is a member of the following [[regulons]] = | ||
| + | {{SubtiWiki regulon|[[SigE regulon]]}}, | ||
| + | {{SubtiWiki regulon|[[SigG regulon]]}} | ||
=The gene= | =The gene= | ||
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=The protein= | =The protein= | ||
Revision as of 23:50, 8 December 2010
- Description: carboxy-terminal processing serine protease, cleaves SpoIVFA, this results in processing of pro-SigK
| Gene name | ctpB |
| Synonyms | yvjB |
| Essential | no |
| Product | carboxy-terminal processing serine protease, cleaves SpoIVFA |
| Function | control of SigK activation |
| MW, pI | 52 kDa, 8.641 |
| Gene length, protein length | 1440 bp, 480 aa |
| Immediate neighbours | swrAA, ftsX |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
proteolysis, sigma factors and their control, sporulation proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU35240
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s): CtpA
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: O35002
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: ctpB (according to DBTBS)
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Nathalie Campo, David Z Rudner
SpoIVB and CtpB are both forespore signals in the activation of the sporulation transcription factor sigmaK in Bacillus subtilis.
J Bacteriol: 2007, 189(16);6021-7
[PubMed:17557826]
[WorldCat.org]
[DOI]
(P p)
Nathalie Campo, David Z Rudner
A branched pathway governing the activation of a developmental transcription factor by regulated intramembrane proteolysis.
Mol Cell: 2006, 23(1);25-35
[PubMed:16818230]
[WorldCat.org]
[DOI]
(P p)
Stephanie T Wang, Barbara Setlow, Erin M Conlon, Jessica L Lyon, Daisuke Imamura, Tsutomu Sato, Peter Setlow, Richard Losick, Patrick Eichenberger
The forespore line of gene expression in Bacillus subtilis.
J Mol Biol: 2006, 358(1);16-37
[PubMed:16497325]
[WorldCat.org]
[DOI]
(P p)
Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190]
[WorldCat.org]
[DOI]
(P p)
Qi Pan, Richard Losick, David Z Rudner
A second PDZ-containing serine protease contributes to activation of the sporulation transcription factor sigmaK in Bacillus subtilis.
J Bacteriol: 2003, 185(20);6051-6
[PubMed:14526016]
[WorldCat.org]
[DOI]
(P p)
