Difference between revisions of "CcdA"
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| + | = [[Categories]] containing this gene/protein = | ||
| + | {{SubtiWiki category|[[respiration]]}}, | ||
| + | {{SubtiWiki category|[[membrane proteins]]}} | ||
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| + | = This gene is a member of the following [[regulons]] = | ||
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=The gene= | =The gene= | ||
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=The protein= | =The protein= | ||
Revision as of 20:05, 8 December 2010
- Description: membrane-embedded thiol-disulfide oxidoreductase
| Gene name | ccdA |
| Synonyms | |
| Essential | no |
| Product | thiol-disulfide oxidoreductase |
| Function | cytochrome c synthesis |
| MW, pI | 25 kDa, 9.667 |
| Gene length, protein length | 705 bp, 235 aa |
| Immediate neighbours | ynzD, yneI |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
respiration, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU17930
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: dsbD family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P45706
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Lýdur S Erlendsson, Lars Hederstedt
Mutations in the thiol-disulfide oxidoreductases BdbC and BdbD can suppress cytochrome c deficiency of CcdA-defective Bacillus subtilis cells.
J Bacteriol: 2002, 184(5);1423-9
[PubMed:11844773]
[WorldCat.org]
[DOI]
(P p)
N E Le Brun, J Bengtsson, L Hederstedt
Genes required for cytochrome c synthesis in Bacillus subtilis.
Mol Microbiol: 2000, 36(3);638-50
[PubMed:10844653]
[WorldCat.org]
[DOI]
(P p)
T Schiött, L Hederstedt
Efficient spore synthesis in Bacillus subtilis depends on the CcdA protein.
J Bacteriol: 2000, 182(10);2845-54
[PubMed:10781554]
[WorldCat.org]
[DOI]
(P p)
T Schiött, M Throne-Holst, L Hederstedt
Bacillus subtilis CcdA-defective mutants are blocked in a late step of cytochrome c biogenesis.
J Bacteriol: 1997, 179(14);4523-9
[PubMed:9226261]
[WorldCat.org]
[DOI]
(P p)
T Schiött, C von Wachenfeldt, L Hederstedt
Identification and characterization of the ccdA gene, required for cytochrome c synthesis in Bacillus subtilis.
J Bacteriol: 1997, 179(6);1962-73
[PubMed:9068642]
[WorldCat.org]
[DOI]
(P p)
