Difference between revisions of "BceA"
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| − | * '''Description:''' bacitracin [[ABC transporter]] (ATP-binding protein) for bacitracin | + | * '''Description:''' bacitracin [[ABC transporter]] (ATP-binding protein) for the export of bacitracin, plectasin, mersacidin and actagardine <br/><br/> |
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|style="background:#ABCDEF;" align="center"| '''Product''' || bacitracin [[ABC transporter]] (ATP-binding protein) | |style="background:#ABCDEF;" align="center"| '''Product''' || bacitracin [[ABC transporter]] (ATP-binding protein) | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || export of toxic peptides |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 28 kDa, 9.287 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 28 kDa, 9.287 | ||
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* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** induced in the presence of bacitracin ([[BceR]]) {{PubMed|12890034}} | + | ** induced in the presence of bacitracin, plectasin, mersacidin and actagardine ([[BceR]]) {{PubMed|12890034}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| Line 120: | Line 120: | ||
=References= | =References= | ||
| − | <pubmed> 17905982 ,18394148,12890034,14651641,10092453, 14612242 </pubmed> | + | <pubmed> 17905982 ,18394148,12890034,14651641,10092453, 14612242 21078927 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 17:41, 17 November 2010
- Description: bacitracin ABC transporter (ATP-binding protein) for the export of bacitracin, plectasin, mersacidin and actagardine
| Gene name | ytsC |
| Synonyms | bceA |
| Essential | no |
| Product | bacitracin ABC transporter (ATP-binding protein) |
| Function | export of toxic peptides |
| MW, pI | 28 kDa, 9.287 |
| Gene length, protein length | 759 bp, 253 aa |
| Immediate neighbours | bceB, bceS |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU30380
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: ABC transporter family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O34697
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Foglino M. PubMed
Your additional remarks
References
Anna Staroń, Dora Elisabeth Finkeisen, Thorsten Mascher
Peptide antibiotic sensing and detoxification modules of Bacillus subtilis.
Antimicrob Agents Chemother: 2011, 55(2);515-25
[PubMed:21078927]
[WorldCat.org]
[DOI]
(I p)
Eva Rietkötter, Diana Hoyer, Thorsten Mascher
Bacitracin sensing in Bacillus subtilis.
Mol Microbiol: 2008, 68(3);768-85
[PubMed:18394148]
[WorldCat.org]
[DOI]
(I p)
Remi Bernard, Annick Guiseppi, Marc Chippaux, Maryline Foglino, François Denizot
Resistance to bacitracin in Bacillus subtilis: unexpected requirement of the BceAB ABC transporter in the control of expression of its own structural genes.
J Bacteriol: 2007, 189(23);8636-42
[PubMed:17905982]
[WorldCat.org]
[DOI]
(I p)
Thorsten Mascher, Neil G Margulis, Tao Wang, Rick W Ye, John D Helmann
Cell wall stress responses in Bacillus subtilis: the regulatory network of the bacitracin stimulon.
Mol Microbiol: 2003, 50(5);1591-604
[PubMed:14651641]
[WorldCat.org]
[DOI]
(P p)
Remi Bernard, Pascale Joseph, Annick Guiseppi, Marc Chippaux, François Denizot
YtsCD and YwoA, two independent systems that confer bacitracin resistance to Bacillus subtilis.
FEMS Microbiol Lett: 2003, 228(1);93-7
[PubMed:14612242]
[WorldCat.org]
[DOI]
(P p)
Reiko Ohki, Giyanto, Kozue Tateno, Waka Masuyama, Shigeki Moriya, Kazuo Kobayashi, Naotake Ogasawara
The BceRS two-component regulatory system induces expression of the bacitracin transporter, BceAB, in Bacillus subtilis.
Mol Microbiol: 2003, 49(4);1135-44
[PubMed:12890034]
[WorldCat.org]
[DOI]
(P p)
Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453]
[WorldCat.org]
[DOI]
(P p)
