Difference between revisions of "SrfAC"

From SubtiWiki
Jump to: navigation, search
(References)
Line 104: Line 104:
 
** [[PerR]]: transcription activation {{PubMed|16166527}}
 
** [[PerR]]: transcription activation {{PubMed|16166527}}
 
** [[Spx]]: transcription repression {{PubMed|12642660}}
 
** [[Spx]]: transcription repression {{PubMed|12642660}}
 +
** [[Abh]]: transcription repression{{PubMed|20817675}}
  
 
* '''Additional information:'''
 
* '''Additional information:'''
Line 129: Line 130:
 
<pubmed>20735481 </pubmed>
 
<pubmed>20735481 </pubmed>
 
==Original publications==
 
==Original publications==
<pubmed>17227471,16166527,8288534,18583577, 17190806,8830686,17218307, 1715856 12642660 16091051 18763711 </pubmed>
+
<pubmed>17227471,16166527,8288534,18583577, 17190806,8830686,17218307, 1715856 12642660 16091051 18763711 20817675</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 06:14, 18 September 2010

  • Description: surfactin synthetase / competence

Gene name srfAC
Synonyms comL
Essential no
Product surfactin synthetase / competence
Function antibiotic synthesis
MW, pI 143 kDa, 4.97
Gene length, protein length 3822 bp, 1274 aa
Immediate neighbours comS, srfAD
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
SrfAC context.gif
This image was kindly provided by SubtiList





The gene

Basic information

  • Locus tag: BSU03510

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: acyl carrier domain (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: phosphorylation on Ser-1003 PubMed
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane PubMed

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
    • repressed during hydrogen peroxide stress (PerR) PubMed
    • expressed at high cell density (ComA) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original publications