Difference between revisions of "Rph"
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| − | * '''Description:''' [[RNase]] PH<br/><br/> | + | * '''Description:''' [[RNase]] PH, 3'-5' exoribonuclease<br/><br/> |
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=== Additional information=== | === Additional information=== | ||
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=The protein= | =The protein= | ||
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=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' tRNA( | + | * '''Catalyzed reaction/ biological activity:''' |
| + | ** major player in the exonucleolytic maturation of CCA-containing tRNA precursors {{PubMed|15983136}} | ||
| + | ** responsible for endonucleolytic cleavage of scRNA (''[[scr]]'') {{PubMed|17576666}} | ||
* '''Protein family:''' [[RNase]] PH family (according to Swiss-Prot) | * '''Protein family:''' [[RNase]] PH family (according to Swiss-Prot) | ||
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=References= | =References= | ||
| − | + | <pubmed>17576666 15805522, 19880604 14767080 1624460 15983136 </pubmed> | |
| − | <pubmed>17576666 15805522, 19880604 14767080 </pubmed> | ||
| − | |||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 17:56, 1 August 2010
- Description: RNase PH, 3'-5' exoribonuclease
| Gene name | rph |
| Synonyms | |
| Essential | no |
| Product | RNase PH (EC 2.7.7.56) |
| Function | 3'-5' exoribonuclease |
| MW, pI | 26 kDa, 4.888 |
| Gene length, protein length | 735 bp, 245 aa |
| Immediate neighbours | ysnA, gerM |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU28370
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: RNase PH family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure: 1OYS
- UniProt: P28619
- KEGG entry: [2]
- E.C. number: 2.7.7.56
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
David Bechhofer, Mount Sinai School, New York, USA Homepage
Ciaran Condon, IBPC, Paris, France Homepage
Your additional remarks
References
