Difference between revisions of "IseA"
| Line 72: | Line 72: | ||
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' [[IseA]]-[[LytF]] (catalytic domain) | + | * '''Interactions:''' [[IseA]]-[[LytF]] (catalytic domain) {{PubMed|18761694}} |
| − | * '''Localization:''' cell membrane (according to Swiss-Prot) | + | * '''Localization:''' cell membrane (according to Swiss-Prot), localized to cell separation sites |
=== Database entries === | === Database entries === | ||
| Line 95: | Line 95: | ||
* '''Regulation:''' | * '''Regulation:''' | ||
| − | * repressed by [[WalR]] {{PubMed|17581128}} | + | ** repressed by [[WalR]] {{PubMed|17581128}} |
| + | ** induced by vancomycin {{PubMed|17483219}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | * [[WalR]]: transcription repression {{PubMed|17581128}} | + | ** [[WalR]]: transcription repression {{PubMed|17581128}} |
* '''Additional information:''' | * '''Additional information:''' | ||
Revision as of 10:32, 1 August 2010
- Description: inhibits in vitro activity of cell wall endopeptidases LytE and LytF, inhibits cell separation
| Gene name | iseA |
| Synonyms | yoeB |
| Essential | no |
| Product | inhibitor of autolysins |
| Function | protection against cell envelope stress |
| MW, pI | 19 kDa, 10.176 |
| Gene length, protein length | 543 bp, 181 aa |
| Immediate neighbours | yoeA, trnSL-Arg1 |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU18380
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane (according to Swiss-Prot), localized to cell separation sites
Database entries
- Structure:
- UniProt: O34841
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
