Difference between revisions of "ThiW"
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=Expression and regulation= | =Expression and regulation= | ||
| − | |||
* '''Operon:''' ''[[thiU]]-[[thiV]]-[[thiW]]-[[thiX]]'' {{PubMed|16291685}} | * '''Operon:''' ''[[thiU]]-[[thiV]]-[[thiW]]-[[thiX]]'' {{PubMed|16291685}} | ||
| Line 97: | Line 96: | ||
* '''Regulation:''' | * '''Regulation:''' | ||
| + | ** repressed by thiamine ([[Thi-box]]) {{PubMed|12376536}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[Thi-box]]: [[RNA switch]] {{PubMed|12376536}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 122: | Line 123: | ||
=References= | =References= | ||
| − | <pubmed>10092453,16291685,, </pubmed> | + | <pubmed>10092453,16291685,12376536, </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 18:55, 12 June 2010
- Description: thiamine ABC transporter (ATP-binding protein)
| Gene name | thiW |
| Synonyms | ykoD |
| Essential | no |
| Product | thiamine ABC transporter (ATP-binding protein) |
| Function | thiamine uptake |
| Metabolic function and regulation of this protein in SubtiPathways: Thiamin | |
| MW, pI | 54 kDa, 5.708 |
| Gene length, protein length | 1470 bp, 490 aa |
| Immediate neighbours | thiX, thiV |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU13220
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: ABC transporter family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O34362
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Ghislain Schyns, Sébastien Potot, Yi Geng, Teresa M Barbosa, Adriano Henriques, John B Perkins
Isolation and characterization of new thiamine-deregulated mutants of Bacillus subtilis.
J Bacteriol: 2005, 187(23);8127-36
[PubMed:16291685]
[WorldCat.org]
[DOI]
(P p)
Dmitry A Rodionov, Alexey G Vitreschak, Andrey A Mironov, Mikhail S Gelfand
Comparative genomics of thiamin biosynthesis in procaryotes. New genes and regulatory mechanisms.
J Biol Chem: 2002, 277(50);48949-59
[PubMed:12376536]
[WorldCat.org]
[DOI]
(P p)
Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453]
[WorldCat.org]
[DOI]
(P p)
