Difference between revisions of "SecG"

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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
* '''Interactions:'''
+
* '''Interactions:''' ([[SecY]]-[[SecE]]-[[SecG]])2-[[SecA]]2
  
 
* '''Localization:''' cell membrane (according to Swiss-Prot)
 
* '''Localization:''' cell membrane (according to Swiss-Prot)
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=== Database entries ===
 
=== Database entries ===
  
* '''Structure:'''
+
* '''Structure:''' [http://www.rcsb.org/pdb/explore/explore.do?pdbId=3DL8 3DL8] (structure of the ([[SecY]]-[[SecE]]-[[SecG]])-[[SecA]] complex) {{PubMed|18923516}}
  
 
* '''UniProt:''' [http://www.uniprot.org/uniprot/O32233 O32233]
 
* '''UniProt:''' [http://www.uniprot.org/uniprot/O32233 O32233]
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=References=
 
=References=
<pubmed>10074070 </pubmed>
+
<pubmed>10074070 18923516</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 10:45, 4 June 2010

  • Description: preprotein translocase subunit

Gene name secG
Synonyms yvaL
Essential no
Product preprotein translocase subunit
Function protein secretion
MW, pI 7 kDa, 10.413
Gene length, protein length 228 bp, 76 aa
Immediate neighbours yvaK, yvaM
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
SecG context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU33630

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

Deletion of secG from the chromosome causes a temperature sensitive secretion defect. PubMed

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: secG family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Jochen Zimmer, Yunsun Nam, Tom A Rapoport
Structure of a complex of the ATPase SecA and the protein-translocation channel.
Nature: 2008, 455(7215);936-43
[PubMed:18923516] [WorldCat.org] [DOI] (I p)

K H van Wely, J Swaving, C P Broekhuizen, M Rose, W J Quax, A J Driessen
Functional identification of the product of the Bacillus subtilis yvaL gene as a SecG homologue.
J Bacteriol: 1999, 181(6);1786-92
[PubMed:10074070] [WorldCat.org] [DOI] (P p)