Difference between revisions of "KinD"
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| − | * '''Description:''' [[two-component systems|two-component]] sensor kinase, phosphorylates [[Spo0F]], part of the [[phosphorelay]] <br/><br/> | + | * '''Description:''' [[two-component systems|two-component]] sensor kinase, phosphorylates [[Spo0F]], part of the [[phosphorelay]], checkpoint protein that links sporulation initiation to the formation of the biofilm matrix <br/><br/> |
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=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' autophosphorylation, phosphorylation of [[Spo0F]] | + | * '''Catalyzed reaction/ biological activity:''' autophosphorylation, phosphorylation of [[Spo0F]], regulates the onset of sporulation by inhibiting the activity of [[Spo0A]] until matrix, or a component therein, is sensed [http://mbio.asm.org/content/1/1/e00035-10.full PubMed] |
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* '''Protein family:''' | * '''Protein family:''' | ||
Revision as of 15:03, 19 May 2010
- Description: two-component sensor kinase, phosphorylates Spo0F, part of the phosphorelay, checkpoint protein that links sporulation initiation to the formation of the biofilm matrix
| Gene name | kinD |
| Synonyms | ykvD |
| Essential | no |
| Product | two-component sensor kinase |
| Function | initiation of sporulation |
| Function and regulation of this protein in SubtiPathways: Phosphorelay | |
| MW, pI | 56 kDa, 6.745 |
| Gene length, protein length | 1518 bp, 506 aa |
| Immediate neighbours | eag, mhqR |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU13660
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: autophosphorylation, phosphorylation of Spo0F, regulates the onset of sporulation by inhibiting the activity of Spo0A until matrix, or a component therein, is sensed PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains: two transmembrane segments, C-terminal histidine phosphotransferase domain
- Modification: autophosphorylation on a His residue
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- Structure: 3FOS
- UniProt: O31671
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
