Difference between revisions of "RplK"

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=References=
 
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<pubmed>11244072, 19653700 </pubmed>
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<pubmed>11244072, 19653700 20441189 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 11:54, 6 May 2010

Gene name rplK
Synonyms relC, tsp
Essential no
Product ribosomal protein L11 (BL11)
Function translation
MW, pI 14 kDa, 9.718
Gene length, protein length 423 bp, 141 aa
Immediate neighbours nusG, rplA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
RplK context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU01020

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure: 1FOX (C-terminal domain, Geobacillus stearothermophilus), 2FOW (RNA binding domain in complex with RNA, Geobacillus stearothermophilus)
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
    • RelA dependent downregulation (Class I) during stringent response PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Sascha Baumann, Sebastian Schoof, Marcel Bolten, Claudia Haering, Motoki Takagi, Kazuo Shin-ya, Hans-Dieter Arndt
Molecular determinants of microbial resistance to thiopeptide antibiotics.
J Am Chem Soc: 2010, 132(20);6973-81
[PubMed:20441189] [WorldCat.org] [DOI] (I p)

Matthew A Lauber, William E Running, James P Reilly
B. subtilis ribosomal proteins: structural homology and post-translational modifications.
J Proteome Res: 2009, 8(9);4193-206
[PubMed:19653700] [WorldCat.org] [DOI] (P p)

S Zhang, J M Scott, W G Haldenwang
Loss of ribosomal protein L11 blocks stress activation of the Bacillus subtilis transcription factor sigma(B).
J Bacteriol: 2001, 183(7);2316-21
[PubMed:11244072] [WorldCat.org] [DOI] (P p)