Difference between revisions of "MutTA"

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<pubmed>16513759,16497325, 14761999, 19011023 9387221 </pubmed>
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<pubmed>16513759,16497325, 14761999, 19011023 9387221 15576788 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 20:10, 3 May 2010

  • Description: error prevention oxidized guanine system, confers protection against oxidative stress to vegetative cells

Gene name mutTA
Synonyms ytkD
Essential no
Product 8-oxo-dGTPase (antimutator)
Function DNA repair
MW, pI 18 kDa, 5.952
Gene length, protein length 474 bp, 158 aa
Immediate neighbours ytlD, ytkC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YtkD context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU30630

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: nucleoside triphosphate + 2H2O = nucleoside monophosphate + 2 phosphate (according to Swiss-Prot)
  • Protein family: Nudix hydrolase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed during logarithmic growth (SigA) and early during sporulation in the forespore (SigF) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References