Difference between revisions of "TrmFO"

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* '''Description:''' tRNA:m(5)U-54 methyltransferase, glucose-inhibited division protein <br/><br/>
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* '''Description:''' flavoprotein, tRNA:m(5)U-54 methyltransferase, glucose-inhibited division protein <br/><br/>
  
 
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=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
* '''Catalyzed reaction/ biological activity:''' 5,10-methylenetetrahydrofolate + tRNA containing uridine at position 54 + FADH<sub>2</sub> = tetrahydrofolate + tRNA containing ribothymidine at position 54 + FAD (according to Swiss-Prot)
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* '''Catalyzed reaction/ biological activity:''' catalyzes the folate-dependent C(5)-methylation of uridine at position 54 in the TpsiC loop of tRNA
  
 
* '''Protein family:''' TrmFO subfamily (according to Swiss-Prot)
 
* '''Protein family:''' TrmFO subfamily (according to Swiss-Prot)
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=References=
 
=References=
<pubmed> 16027442 </pubmed>
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<pubmed> 16027442 20412857 </pubmed>
 
 
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 08:49, 24 April 2010

  • Description: flavoprotein, tRNA:m(5)U-54 methyltransferase, glucose-inhibited division protein

Gene name trmFO
Synonyms ylyC, gid
Essential no
Product tRNA:m(5)U-54 methyltransferase
Function tRNA modification
MW, pI 47 kDa, 5.767
Gene length, protein length 1305 bp, 435 aa
Immediate neighbours topA, codV
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
Gid context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU16130

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: catalyzes the folate-dependent C(5)-methylation of uridine at position 54 in the TpsiC loop of tRNA
  • Protein family: TrmFO subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References