Difference between revisions of "PhrC"
| Line 99: | Line 99: | ||
** repressed during growth in the presence of branched chain amino acids ([[CodY]]) {{PubMed|10464187}} | ** repressed during growth in the presence of branched chain amino acids ([[CodY]]) {{PubMed|10464187}} | ||
** repressed by glucose (4.5-fold) ([[CcpA]]) [http://www.ncbi.nlm.nih.gov/pubmed/12850135 PubMed] | ** repressed by glucose (4.5-fold) ([[CcpA]]) [http://www.ncbi.nlm.nih.gov/pubmed/12850135 PubMed] | ||
| + | ** expressed at high cell density ([[ComA]]) {{PubMed|16091051}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[ComA]]: transcription activation ([[ComA]]) {{PubMed|16091051}} | ||
** [[CodY]]: transcription repression {{PubMed|10464187}} | ** [[CodY]]: transcription repression {{PubMed|10464187}} | ||
| − | |||
** [[CcpA]]: transcription repression [http://www.ncbi.nlm.nih.gov/pubmed/12850135 PubMed] | ** [[CcpA]]: transcription repression [http://www.ncbi.nlm.nih.gov/pubmed/12850135 PubMed] | ||
| Line 127: | Line 128: | ||
=References= | =References= | ||
| − | <pubmed>12950917,16816200,19202088,18375560 ,11267663,10464187,12850135, </pubmed> | + | <pubmed>12950917,16816200,19202088,18375560 ,11267663,10464187,12850135,16091051 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 20:00, 15 February 2010
- Description: response regulator aspartate phosphatase (RapC) regulator / competence and sporulation stimulating factor (CSF)
| Gene name | phrC |
| Synonyms | |
| Essential | no |
| Product | phosphatase (RapC) regulator / competence and sporulation stimulating factor (CSF) |
| Function | control of ComA activity |
| MW, pI | 4 kDa, 8.16 |
| Gene length, protein length | 120 bp, 40 aa |
| Immediate neighbours | rapC, yclM |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU03780
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: binds to RapC, this results in the inability of RapC to interact with ComA PubMed
- Protein family: phr family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- Structure:
- UniProt: P94416
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
