Difference between revisions of "RapC"
| Line 94: | Line 94: | ||
* '''Regulation:''' | * '''Regulation:''' | ||
** repressed during growth in the presence of branched chain amino acids ([[CodY]]) {{PubMed|10464187}} | ** repressed during growth in the presence of branched chain amino acids ([[CodY]]) {{PubMed|10464187}} | ||
| + | ** expressed at high cell density ([[ComA]]) {{PubMed|16091051}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[ComA]]: transcription activation ([[ComA]]) {{PubMed|16091051}} | ||
** [[CodY]]: transcription repression {{PubMed|10464187}} | ** [[CodY]]: transcription repression {{PubMed|10464187}} | ||
| − | |||
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 121: | Line 122: | ||
=References= | =References= | ||
| − | <pubmed>12950917,,10464187, </pubmed> | + | <pubmed>12950917,16091051,10464187, </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 19:58, 15 February 2010
- Description: response regulator aspartate phosphatase, controls ComA activity
| Gene name | rapC |
| Synonyms | yclL |
| Essential | no |
| Product | response regulator aspartate phosphatase |
| Function | control of ComA activity |
| MW, pI | 45 kDa, 5.024 |
| Gene length, protein length | 1146 bp, 382 aa |
| Immediate neighbours | yclK, phrC |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU03770
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Protein family: RAP family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Localization:
Database entries
- Structure:
- UniProt: P94415
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Natalia Comella, Alan D Grossman
Conservation of genes and processes controlled by the quorum response in bacteria: characterization of genes controlled by the quorum-sensing transcription factor ComA in Bacillus subtilis.
Mol Microbiol: 2005, 57(4);1159-74
[PubMed:16091051]
[WorldCat.org]
[DOI]
(P p)
Leighton Core, Marta Perego
TPR-mediated interaction of RapC with ComA inhibits response regulator-DNA binding for competence development in Bacillus subtilis.
Mol Microbiol: 2003, 49(6);1509-22
[PubMed:12950917]
[WorldCat.org]
[DOI]
(P p)
B A Lazazzera, I G Kurtser, R S McQuade, A D Grossman
An autoregulatory circuit affecting peptide signaling in Bacillus subtilis.
J Bacteriol: 1999, 181(17);5193-200
[PubMed:10464187]
[WorldCat.org]
[DOI]
(P p)
