Difference between revisions of "Dra"
| Line 89: | Line 89: | ||
=Expression and regulation= | =Expression and regulation= | ||
| + | * '''Operon:''' ''[[dra]]-[[nupC]]-[[pdp]]'' {{PubMed|8550462}} | ||
| − | * ''' | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|8550462}} |
| − | * '''[[ | + | * '''Regulation:''' |
| + | ** repressed by glucose ([[CcpA]]) {{PubMed|10666464}} | ||
| + | ** induced by deoxynucleotides ([[DeoR]]) {{PubMed|8550462}} | ||
| − | * ''' | + | * '''Regulatory mechanism:''' |
| − | + | ** [[CcpA]]: transcription repression {{PubMed|10666464}} | |
| − | * | + | ** [[DeoR]]: transcription repression {{PubMed|8550462}} |
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 119: | Line 122: | ||
=References= | =References= | ||
| − | + | <pubmed>10666464,11065368,8550462,10074062, </pubmed> | |
| − | <pubmed>,11065368,8550462,10074062, </pubmed> | ||
| − | |||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 19:22, 8 February 2010
- Description: deoxyribose-phosphate aldolase
| Gene name | dra |
| Synonyms | |
| Essential | no |
| Product | deoxyribose-phosphate aldolase |
| Function | utilization of nucleotides as carbon source |
| Metabolic function and regulation of this protein in SubtiPathways: Nucleoside catabolism, Nucleotides (regulation) | |
| MW, pI | 22 kDa, 4.926 |
| Gene length, protein length | 633 bp, 211 aa |
| Immediate neighbours | nupC, deoR |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU39420
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde (according to Swiss-Prot)
- Protein family: DeoC type 1 subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P39121
- KEGG entry: [3]
- E.C. number: 4.1.2.4
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
