Difference between revisions of "CapB"
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=Expression and regulation= | =Expression and regulation= | ||
− | * '''Operon:''' ''[[capB]]-[[capC]]-[[capA]]-[[ | + | * '''Operon:''' ''[[capB]]-[[capC]]-[[capA]]-[[capE]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/11751809 PubMed] |
* '''Sigma factor:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/19420703 PubMed] | * '''Sigma factor:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/19420703 PubMed] |
Revision as of 10:58, 9 January 2010
- Description: capsular polyglutamate biosynthesis
Gene name | capB |
Synonyms | ywsC, pgsB |
Essential | no |
Product | poly-gamma-glutamate synthetase |
Function | capsule synthesis |
MW, pI | 43 kDa, 5.073 |
Gene length, protein length | 1179 bp, 393 aa |
Immediate neighbours | capC, rbsR |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU35900
Phenotypes of a mutant
no synthesis of the poly-gamma-glutamate capsule PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: synthesis of poly-gamma-glutamate from L-Glu PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P96736
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Additional information: The operon is not expressed in the lab strain 168 due to lack of expression of DegQ resulting in inactivity of DegS and DegU
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References