Difference between revisions of "BacG"

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(Basic information/ Evolution)
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=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
* '''Catalyzed reaction/ biological activity:'''  
+
* '''Catalyzed reaction/ biological activity:''' YwfH catalyzes the conjugate addition of hydride at the C4 olefinic terminus using NADH to yield the cyclohexenol- containing tetrahydro-4-hydroxyphenylpyruvate {{PubMed|20052993}}
  
 
* '''Protein family:''' short-chain dehydrogenases/reductases (SDR) family (according to Swiss-Prot)
 
* '''Protein family:''' short-chain dehydrogenases/reductases (SDR) family (according to Swiss-Prot)

Revision as of 10:20, 8 January 2010

  • Description: similar to 3-oxoacyl- acyl-carrier protein reductase

Gene name ywfH
Synonyms ipa-86r
Essential no
Product unknown
Function biosynthesis of the antibiotic bacilysin
MW, pI 27 kDa, 6.596
Gene length, protein length 777 bp, 259 aa
Immediate neighbours ywfI, bacF
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YwfH context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU37680

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: YwfH catalyzes the conjugate addition of hydride at the C4 olefinic terminus using NADH to yield the cyclohexenol- containing tetrahydro-4-hydroxyphenylpyruvate PubMed
  • Protein family: short-chain dehydrogenases/reductases (SDR) family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed by casamino acids PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References