Difference between revisions of "YvcL"
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=== Database entries === | === Database entries === | ||
| − | * '''Structure:''' | + | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=3HYI 3HYI] (Crystal structure of full-length DUF199/WhiA from Thermatoga maritima), [http://www.rcsb.org/pdb/explore.do?structureId=3HYJ 3HYJ] (Crystal structure of the N-terminal LAGLIDADG domain of DUF199/WhiA) |
* '''UniProt:''' [http://www.uniprot.org/uniprot/O06975 O06975] | * '''UniProt:''' [http://www.uniprot.org/uniprot/O06975 O06975] | ||
Revision as of 20:05, 20 December 2009
- Description: WhiA family protein conserved and ubiquitous among gram-positive bacteria with unknown function
| Gene name | yvcL |
| Synonyms | |
| Essential | no |
| Product | unknown |
| Function | unknown |
| MW, pI | 36 kDa, 9.479 |
| Gene length, protein length | 948 bp, 316 aa |
| Immediate neighbours | crh, yvcK |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU34750
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: WhiA family PubMed
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains: suggested HTH domain PubMed
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure: 3HYI (Crystal structure of full-length DUF199/WhiA from Thermatoga maritima), 3HYJ (Crystal structure of the N-terminal LAGLIDADG domain of DUF199/WhiA)
- UniProt: O06975
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Regulation: very weak stimuation of expression by citrate and succinate PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Boris Görke, Elodie Foulquier, Anne Galinier
YvcK of Bacillus subtilis is required for a normal cell shape and for growth on Krebs cycle intermediates and substrates of the pentose phosphate pathway.
Microbiology (Reading): 2005, 151(Pt 11);3777-3791
[PubMed:16272399]
[WorldCat.org]
[DOI]
(P p)
A Galinier, J Haiech, M C Kilhoffer, M Jaquinod, J Stülke, J Deutscher, I Martin-Verstraete
The Bacillus subtilis crh gene encodes a HPr-like protein involved in carbon catabolite repression.
Proc Natl Acad Sci U S A: 1997, 94(16);8439-44
[PubMed:9237995]
[WorldCat.org]
[DOI]
(P p)
