Difference between revisions of "MenC"
| Line 80: | Line 80: | ||
=== Database entries === | === Database entries === | ||
| − | * ''' | + | * '''Structure:''' |
* '''UniProt:''' [http://www.uniprot.org/uniprot/O34514 O34514] | * '''UniProt:''' [http://www.uniprot.org/uniprot/O34514 O34514] | ||
| Line 97: | Line 97: | ||
* '''[[Sigma factor]]:''' | * '''[[Sigma factor]]:''' | ||
| − | ** ''[[menF]]'': {{PubMed|8550504}} | + | ** ''[[menF]]'': [[SigA]] {{PubMed|8550504}} |
| − | ** ''[[menB]]'': {{PubMed|9387221,1629163}} | + | ** ''[[menB]]'': [[SigA]] {{PubMed|9387221,1629163}} |
| − | ** ''[[menE]]'': {{PubMed|9387221,1629163}} | + | ** ''[[menE]]'': [[SigA]] {{PubMed|9387221,1629163}} |
* '''Regulation:''' | * '''Regulation:''' | ||
Revision as of 21:04, 19 December 2009
- Description: O-succinylbenzoate-CoA synthase
| Gene name | menC |
| Synonyms | ytfD |
| Essential | yes PubMed |
| Product | O-succinylbenzoate-CoA synthase |
| Function | biosynthesis of menaquinone |
| Metabolic function and regulation of this protein in SubtiPathways: Menaquinone | |
| MW, pI | 41 kDa, 5.888 |
| Gene length, protein length | 1113 bp, 371 aa |
| Immediate neighbours | mntA, menE |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU30780
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate = 2-succinylbenzoate + H2O (according to Swiss-Prot)
- Protein family: mandelate racemase/muconate lactonizing enzyme family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: O34514
- KEGG entry: [3]
- E.C. number: 4.2.1.113
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Alia Lapidus, Nathalie Galleron, Alexei Sorokin, S Dusko Ehrlich
Sequencing and functional annotation of the Bacillus subtilis genes in the 200 kb rrnB-dnaB region.
Microbiology (Reading): 1997, 143 ( Pt 11);3431-3441
[PubMed:9387221]
[WorldCat.org]
[DOI]
(P p)
X Qin, H W Taber
Transcriptional regulation of the Bacillus subtilis menp1 promoter.
J Bacteriol: 1996, 178(3);705-13
[PubMed:8550504]
[WorldCat.org]
[DOI]
(P p)
J R Driscoll, H W Taber
Sequence organization and regulation of the Bacillus subtilis menBE operon.
J Bacteriol: 1992, 174(15);5063-71
[PubMed:1629163]
[WorldCat.org]
[DOI]
(P p)
