Difference between revisions of "RapH"
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| − | * '''Description:''' response regulator aspartate phosphatase <br/><br/> | + | * '''Description:''' response regulator aspartate phosphatase, dephosphorylates [[Spo0F]]-P, control of the [[phosphorelay]], control of [[ComA]] activity <br/><br/> |
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|style="background:#ABCDEF;" align="center"| '''Product''' || response regulator aspartate phosphatase | |style="background:#ABCDEF;" align="center"| '''Product''' || response regulator aspartate phosphatase | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || control of sporulation initiation | + | |style="background:#ABCDEF;" align="center"|'''Function''' || control of sporulation initiation and [[ComA]] activity |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 49 kDa, 6.121 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 49 kDa, 6.121 | ||
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=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' binds to and thereby inhibits [[ComA]] activity {{PubMed|17581123}}; in addition, RapH dephosphorylates [[Spo0F]]-P and thereby controls the [[phosphorelay]] {{PubMed|17581123}} |
* '''Protein family:''' RAP family (according to Swiss-Prot) | * '''Protein family:''' RAP family (according to Swiss-Prot) | ||
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* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' | + | * '''Interactions:''' [[RapH]]-[[ComA]] {{PubMed|17581123}}, [[RapH]]-[[Spo0F]]-P {{PubMed|17581123}} |
* '''Localization:''' | * '''Localization:''' | ||
Revision as of 11:23, 29 November 2009
- Description: response regulator aspartate phosphatase, dephosphorylates Spo0F-P, control of the phosphorelay, control of ComA activity
| Gene name | rapH |
| Synonyms | yeeH, yzqA |
| Essential | no |
| Product | response regulator aspartate phosphatase |
| Function | control of sporulation initiation and ComA activity |
| MW, pI | 49 kDa, 6.121 |
| Gene length, protein length | 1293 bp, 431 aa |
| Immediate neighbours | yeeG, yeeI |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU06830
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: binds to and thereby inhibits ComA activity PubMed; in addition, RapH dephosphorylates Spo0F-P and thereby controls the phosphorelay PubMed
- Protein family: RAP family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- Structure:
- UniProt: P40771
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: rapH PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Kentaro Hayashi, Tsukahara Kensuke, Kazuo Kobayashi, Naotake Ogasawara, Mitsuo Ogura
Bacillus subtilis RghR (YvaN) represses rapG and rapH, which encode inhibitors of expression of the srfA operon.
Mol Microbiol: 2006, 59(6);1714-29
[PubMed:16553878]
[WorldCat.org]
[DOI]
(P p)
