Difference between revisions of "LutR"

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(References)
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || transcriptional repressor
+
|style="background:#ABCDEF;" align="center"| '''Product''' || transcriptional repressor, ([[GntR family]])
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Function''' || control of lactate utilization
 
|style="background:#ABCDEF;" align="center"|'''Function''' || control of lactate utilization
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* '''Catalyzed reaction/ biological activity:''' transcriptional repressor of the'' [[lutA]]-[[lutB]]-[[lutC]]'' operon [http://www.ncbi.nlm.nih.gov/sites/entrez/19201793 PubMed]
 
* '''Catalyzed reaction/ biological activity:''' transcriptional repressor of the'' [[lutA]]-[[lutB]]-[[lutC]]'' operon [http://www.ncbi.nlm.nih.gov/sites/entrez/19201793 PubMed]
  
* '''Protein family:''' GntR family of transcription factors
+
* '''Protein family:''' [[GntR family]] of transcription factors
  
 
* '''Paralogous protein(s):'''
 
* '''Paralogous protein(s):'''

Revision as of 19:12, 27 November 2009

Gene name lutR
Synonyms yvfI
Essential no
Product transcriptional repressor, (GntR family)
Function control of lactate utilization
Metabolic function and regulation of this protein in SubtiPathways:
Central C-metabolism
MW, pI 19 kDa, 4.845
Gene length, protein length 525 bp, 175 aa
Immediate neighbours lacR, lutP
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YvfI context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU34180

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: transcriptional repressor of the lutA-lutB-lutC operon PubMed
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: lactate acts as molecular inducer PubMed
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Richard Losick, Harvard Univ., Cambridge, USA homepage

Your additional remarks

References

Yunrong Chai, Roberto Kolter, Richard Losick
A widely conserved gene cluster required for lactate utilization in Bacillus subtilis and its involvement in biofilm formation.
J Bacteriol: 2009, 191(8);2423-30
[PubMed:19201793] [WorldCat.org] [DOI] (I p)

Türkan Ebru Köroğlu, Günseli Kurt-Gür, Emine Canan Unlü, Ayten Yazgan-Karataş
The novel gene yvfI in Bacillus subtilis is essential for bacilysin biosynthesis.
Antonie Van Leeuwenhoek: 2008, 94(3);471-9
[PubMed:18604637] [WorldCat.org] [DOI] (P p)