Difference between revisions of "PstA"
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* '''[[Sigma factor]]:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/9098050 PubMed] | * '''[[Sigma factor]]:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/9098050 PubMed] | ||
| − | * '''Regulation:''' expressed under conditions of phosphate limitation (5000-fold induced) | + | * '''Regulation:''' expressed under conditions of phosphate limitation (5000-fold induced) ([[PhoP]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/9098050,9593301 PubMed] |
| − | |||
| − | * '''Regulatory mechanism:''' | + | * '''Regulatory mechanism:''' |
** [[PhoP]]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/9098050,9593301 PubMed] | ** [[PhoP]]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/9098050,9593301 PubMed] | ||
| − | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
Revision as of 21:14, 20 November 2009
- Description: phosphate ABC transporter (permease)
| Gene name | pstA |
| Synonyms | yqgI, yzmD |
| Essential | no |
| Product | phosphate ABC transporter (permease) |
| Function | high-affinity phosphate uptake |
| MW, pI | 31 kDa, 9.303 |
| Gene length, protein length | 882 bp, 294 aa |
| Immediate neighbours | pstBA, pstC |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU24970
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: CysTW subfamily (according to Swiss-Prot)
- Paralogous protein(s): PstC
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P46340
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Marion Hulett, University of Illinois at Chicago, USA Homepage
Your additional remarks
References
Nicholas E E Allenby, Nicola O'Connor, Zoltán Prágai, Noel M Carter, Marcus Miethke, Susanne Engelmann, Michael Hecker, Anil Wipat, Alan C Ward, Colin R Harwood
Post-transcriptional regulation of the Bacillus subtilis pst operon encoding a phosphate-specific ABC transporter.
Microbiology (Reading): 2004, 150(Pt 8);2619-2628
[PubMed:15289558]
[WorldCat.org]
[DOI]
(P p)
Akram Atalla, Wolfgang Schumann
The pst operon of Bacillus subtilis is specifically induced by alkali stress.
J Bacteriol: 2003, 185(16);5019-22
[PubMed:12897025]
[WorldCat.org]
[DOI]
(P p)
Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453]
[WorldCat.org]
[DOI]
(P p)
W Liu, Y Qi, F M Hulett
Sites internal to the coding regions of phoA and pstS bind PhoP and are required for full promoter activity.
Mol Microbiol: 1998, 28(1);119-30
[PubMed:9593301]
[WorldCat.org]
[DOI]
(P p)
Y Qi, Y Kobayashi, F M Hulett
The pst operon of Bacillus subtilis has a phosphate-regulated promoter and is involved in phosphate transport but not in regulation of the pho regulon.
J Bacteriol: 1997, 179(8);2534-9
[PubMed:9098050]
[WorldCat.org]
[DOI]
(P p)
