Difference between revisions of "MgsR"

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* '''Description:''' transcriptional regulator of a subset of the SigB general stress regulon <br/><br/>
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* '''Description:''' transcriptional regulator of a subset of the [[SigB]] general stress regulon <br/><br/>
  
 
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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:'''  
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* '''Operon:''' ''mgsR'' (according to [http://dbtbs.hgc.jp/COG/prom/yqgZ.html DBTBS])
  
* '''[[Sigma factor]]:''' [[SigB]] [http://www.ncbi.nlm.nih.gov/sites/entrez/18643936 PubMed]
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* '''[[Sigma factor]]:''' [[SigB]] {{PubMed|18643936}}
  
* '''Regulation:''' repressed by casamino acids [http://www.ncbi.nlm.nih.gov/pubmed/12107147 PubMed] induced by stress ([[SigB]]) [http://www.ncbi.nlm.nih.gov/pubmed/15805528 PubMed], expressed under stress conditions [http://www.ncbi.nlm.nih.gov/sites/entrez/18643936 PubMed]
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* '''Regulation:'''  
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** repressed by casamino acids [http://www.ncbi.nlm.nih.gov/pubmed/12107147 PubMed]  
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** induced by stress ([[SigB]]) {{PubMed|15805528,18643936}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  

Revision as of 21:04, 20 November 2009

  • Description: transcriptional regulator of a subset of the SigB general stress regulon

Gene name mgsR
Synonyms yqgZ
Essential no
Product transcriptional regulator
Function controls a subset of general stress genes
MW, pI 14 kDa, 9.28
Gene length, protein length 378 bp, 126 aa
Immediate neighbours trnSL-Gln1, yqgY
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YqgZ context.gif
This image was kindly provided by SubtiList





The gene

Basic information

  • Locus tag: BSU24770

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: exerts a positive or negative effect on the expression of 53 or 18 stress genes, respectively PubMed
  • Protein family: arsC family (according to Swiss-Prot) Arsenate Reductase (ArsC) family, Spx subfamily
  • Paralogous protein(s): Spx

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: mgsR (according to DBTBS)
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References