Difference between revisions of "YtvA"

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* '''Description:''' positive regulation of SigB activity under conditions of blue light <br/><br/>
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* '''Description:''' positive regulation of [[SigB]] activity under conditions of blue light <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Product''' || blue light receptor, flavoprotein  
 
|style="background:#ABCDEF;" align="center"| '''Product''' || blue light receptor, flavoprotein  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || control of SigB activity
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|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[SigB]] activity
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 29 kDa, 4.69   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 29 kDa, 4.69   
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=References=
 
=References=
  
<pubmed> 19581299 16923906,17575448, 17764689, 17443319 17200735 16923909 16797012 16022561 15339223 11964249 11157946 </pubmed>
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<pubmed> 19581299 16923906,17575448, 17764689, 17443319 17200735 16923909 16797012 16022561 15339223 11964249 11157946 19891470 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 12:55, 7 November 2009

  • Description: positive regulation of SigB activity under conditions of blue light

Gene name ytvA
Synonyms
Essential no
Product blue light receptor, flavoprotein
Function control of SigB activity
MW, pI 29 kDa, 4.69
Gene length, protein length 783 bp, 261 aa
Immediate neighbours ytvB, yttB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YtvA context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU30340

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Susanne Salzmann, Mario R Silva-Junior, Walter Thiel, Christel M Marian
Influence of the LOV domain on low-lying excited states of flavin: a combined quantum-mechanics/molecular-mechanics investigation.
J Phys Chem B: 2009, 113(47);15610-8
[PubMed:19891470] [WorldCat.org] [DOI] (I p)

Marcela Avila-Pérez, Jocelyne Vreede, Yifen Tang, Onno Bende, Aba Losi, Wolfgang Gärtner, Klaas Hellingwerf
In vivo mutational analysis of YtvA from Bacillus subtilis: mechanism of light activation of the general stress response.
J Biol Chem: 2009, 284(37);24958-64
[PubMed:19581299] [WorldCat.org] [DOI] (I p)

Andreas Möglich, Keith Moffat
Structural basis for light-dependent signaling in the dimeric LOV domain of the photosensor YtvA.
J Mol Biol: 2007, 373(1);112-26
[PubMed:17764689] [WorldCat.org] [DOI] (P p)

Noriko Suzuki, Naoki Takaya, Takayuki Hoshino, Akira Nakamura
Enhancement of a sigma(B)-dependent stress response in Bacillus subtilis by light via YtvA photoreceptor.
J Gen Appl Microbiol: 2007, 53(2);81-8
[PubMed:17575448] [WorldCat.org] [DOI] (P p)

Valentina Buttani, Wolfgang Gärtner, Aba Losi
NTP-binding properties of the blue-light receptor YtvA and effects of the E105L mutation.
Eur Biophys J: 2007, 36(7);831-9
[PubMed:17443319] [WorldCat.org] [DOI] (P p)

Valentina Buttani, Aba Losi, Thorsten Eggert, Ulrich Krauss, Karl-Erich Jaeger, Zhen Cao, Wolfgang Gärtner
Conformational analysis of the blue-light sensing protein YtvA reveals a competitive interface for LOV-LOV dimerization and interdomain interactions.
Photochem Photobiol Sci: 2007, 6(1);41-9
[PubMed:17200735] [WorldCat.org] [DOI] (P p)

Marcela Avila-Pérez, Klaas J Hellingwerf, Remco Kort
Blue light activates the sigmaB-dependent stress response of Bacillus subtilis via YtvA.
J Bacteriol: 2006, 188(17);6411-4
[PubMed:16923909] [WorldCat.org] [DOI] (P p)

Tatiana A Gaidenko, Tae-Jong Kim, Andrea L Weigel, Margaret S Brody, Chester W Price
The blue-light receptor YtvA acts in the environmental stress signaling pathway of Bacillus subtilis.
J Bacteriol: 2006, 188(17);6387-95
[PubMed:16923906] [WorldCat.org] [DOI] (P p)

Valentina Buttani, Aba Losi, Eugenia Polverini, Wolfgang Gärtner
Blue news: NTP binding properties of the blue-light sensitive YtvA protein from Bacillus subtilis.
FEBS Lett: 2006, 580(16);3818-22
[PubMed:16797012] [WorldCat.org] [DOI] (P p)

Aba Losi, Elisa Ghiraldelli, Sven Jansen, Wolfgang Gärtner
Mutational effects on protein structural changes and interdomain interactions in the blue-light sensing LOV protein YtvA.
Photochem Photobiol: 2005, 81(5);1145-52
[PubMed:16022561] [WorldCat.org] [DOI] (P p)

Aba Losi, Elena Ternelli, Wolfgang Gärtner
Tryptophan fluorescence in the Bacillus subtilis phototropin-related protein YtvA as a marker of interdomain interaction.
Photochem Photobiol: 2004, 80;150-3
[PubMed:15339223] [WorldCat.org] [DOI] (P p)

Aba Losi, Eugenia Polverini, Benjamin Quest, Wolfgang Gärtner
First evidence for phototropin-related blue-light receptors in prokaryotes.
Biophys J: 2002, 82(5);2627-34
[PubMed:11964249] [WorldCat.org] [DOI] (P p)

S Akbar, T A Gaidenko, C M Kang, M O'Reilly, K M Devine, C W Price
New family of regulators in the environmental signaling pathway which activates the general stress transcription factor sigma(B) of Bacillus subtilis.
J Bacteriol: 2001, 183(4);1329-38
[PubMed:11157946] [WorldCat.org] [DOI] (P p)