Difference between revisions of "BglP"
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| − | * '''Description:''' [[trigger enzymes|trigger enzyme]]: beta-glucoside-specific phosphotransferase system, EIIBC <br/><br/> | + | * '''Description:''' [[trigger enzymes|trigger enzyme]]: beta-glucoside-specific [[PTS|phosphotransferase system]], EIIBC <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 10: | Line 10: | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || [[trigger enzymes|trigger enzyme]]: beta-glucoside-specific <br/>phosphotransferase system, EIIBC | + | |style="background:#ABCDEF;" align="center"| '''Product''' || [[trigger enzymes|trigger enzyme]]: beta-glucoside-specific <br/>[[PTS|phosphotransferase system]], EIIBC |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || beta-glucoside uptake and phosphorylation, <br/>control of [[LicT]] activity | |style="background:#ABCDEF;" align="center"|'''Function''' || beta-glucoside uptake and phosphorylation, <br/>control of [[LicT]] activity | ||
| Line 94: | Line 94: | ||
* '''Operon:''' ''[[bglP]]-[[bglH]]-[[yxiE]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/7883710 PubMed] | * '''Operon:''' ''[[bglP]]-[[bglH]]-[[yxiE]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/7883710 PubMed] | ||
| − | * '''[[Sigma factor]]:''' [[SigA]] | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|7559347}} |
* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** repressed by glucose ([[CcpA]], [[LicT]]) | + | ** repressed by glucose ([[CcpA]], [[LicT]]) {{PubMed|7559347}} |
** induced by salicin ([[LicT]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/7883710 PubMed] | ** induced by salicin ([[LicT]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/7883710 PubMed] | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | ** [[CcpA]]: transcription repression, ([[CcpA]] binding site overlaps -35 region) | + | ** [[CcpA]]: transcription repression, ([[CcpA]] binding site overlaps -35 region) {{PubMed|7559347}} |
| − | ** [[LicT]]-dependent [[RNA switch]] (antitermination, lack of [[LicT]]-dependent antitermination in the presence of gucose due to the requirement of [[LicT]] to be phosphorylated by [[PtsH| HPr]] | + | ** [[LicT]]-dependent [[RNA switch]] (antitermination, lack of [[LicT]]-dependent antitermination in the presence of gucose due to the requirement of [[LicT]] to be phosphorylated by [[PtsH| HPr]] {{PubMed|8626332}} |
* '''Additional information:''' | * '''Additional information:''' | ||
Revision as of 19:41, 31 October 2009
- Description: trigger enzyme: beta-glucoside-specific phosphotransferase system, EIIBC
| Gene name | bglP |
| Synonyms | sytA |
| Essential | no |
| Product | trigger enzyme: beta-glucoside-specific phosphotransferase system, EIIBC |
| Function | beta-glucoside uptake and phosphorylation, control of LicT activity |
| Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism | |
| MW, pI | 64 kDa, 6.809 |
| Gene length, protein length | 1827 bp, 609 aa |
| Immediate neighbours | bglH, yxxE |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU39270
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Protein EIIA N(pi)-phospho-L-histidine + protein EIIB = protein EIIA + protein EIIB N(pi)-phospho-L-histidine/cysteine (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P40739
- KEGG entry: [3]
- E.C. number: 2.7.1.69 9
Additional information
Expression and regulation
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant: GP475 (erm), available in the Stülke lab
- Expression vector:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
