Difference between revisions of "CheD"
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| − | * '''Description:''' required for methylation of methyl-accepting chemotaxis proteins by CheR, enhances phosphatase activity of CheC <br/><br/> | + | * '''Description:''' required for methylation of methyl-accepting chemotaxis proteins by [[CheR]], enhances phosphatase activity of [[CheC]] <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 10: | Line 10: | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || CheC activity modulator | + | |style="background:#ABCDEF;" align="center"| '''Product''' || [[CheC]] activity modulator |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || motility, chemotaxis | |style="background:#ABCDEF;" align="center"|'''Function''' || motility, chemotaxis | ||
| Line 88: | Line 88: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''[[flgB]]-[[flgC]]-[[fliE]]-[[fliF]]-[[fliG]]-[[fliH]]-[[fliI]]-[[fliJ]]-[[ylxF]]-[[fliK]]-[[ylxG]]-[[flgE]]-[[fliL]]-[[fliM]]-[[fliY]]-[[cheY]]-[[fliZ]]-[[fliP]]-[[fliQ]]-[[fliR]]-[[flhB]]-[[flhA]]-[[flhF]]-[[ylxH]]-[[cheB]]-[[cheA]]-[[cheW]]-[[cheC]]-[[cheD]]-[[sigD]]-[[ylxL]]'' {{PubMed|9657996,8157612,15175317}} |
| − | * '''[[Sigma factor]]:''' [[SigD]] | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|9657996}}, [[SigD]] {{PubMed|9657996}} |
* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** repressed under conditions that trigger sporulation ([[Spo0A]]) | + | ** repressed under conditions that trigger sporulation ([[Spo0A]]) {{PubMed|14651647}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | ** [[Spo0A]]: transcription repression | + | ** [[Spo0A]]: transcription repression {{PubMed|14651647}} |
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 120: | Line 120: | ||
=References= | =References= | ||
| − | <pubmed>7893679,15317802,17908686,12011078,18774298,8866475,11722727,9194713,14651647, </pubmed> | + | <pubmed>7893679,15317802,17908686,12011078,18774298,8866475,11722727,9194713,14651647, 9657996,8157612,15175317</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 17:44, 11 October 2009
- Description: required for methylation of methyl-accepting chemotaxis proteins by CheR, enhances phosphatase activity of CheC
| Gene name | cheD |
| Synonyms | ylxK |
| Essential | no |
| Product | CheC activity modulator |
| Function | motility, chemotaxis |
| MW, pI | 17 kDa, 9.347 |
| Gene length, protein length | 498 bp, 166 aa |
| Immediate neighbours | cheC, sigD |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU16460
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Protein L-glutamine + H2O = protein L-glutamate + NH3 (according to Swiss-Prot)
- Protein family: cheD family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- Structure:
- UniProt: P40404
- KEGG entry: [3]
- E.C. number: 3.5.1.44
Additional information
Expression and regulation
- Operon: flgB-flgC-fliE-fliF-fliG-fliH-fliI-fliJ-ylxF-fliK-ylxG-flgE-fliL-fliM-fliY-cheY-fliZ-fliP-fliQ-fliR-flhB-flhA-flhF-ylxH-cheB-cheA-cheW-cheC-cheD-sigD-ylxL PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
