Difference between revisions of "SplA"
| Line 12: | Line 12: | ||
|style="background:#ABCDEF;" align="center"| '''Product''' || transcriptional regulator | |style="background:#ABCDEF;" align="center"| '''Product''' || transcriptional regulator | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of the | + | |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of the ''[[splA]]-[[splB]]'' operon |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 9 kDa, 4.419 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 9 kDa, 4.419 | ||
| Line 88: | Line 88: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''[[splA]]-[[splB]]'' {{PubMed|8021181}} |
| − | * '''[[Sigma factor]]:''' [[SigG]] {{PubMed|15699190}} | + | * '''[[Sigma factor]]:''' [[SigG]] {{PubMed|15699190,8021181}} |
* '''Regulation:''' | * '''Regulation:''' | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** negative autoregulation by [[SplA]] {{PubMed|8021181}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 117: | Line 118: | ||
=References= | =References= | ||
| − | + | <pubmed> 15699190,8021181</pubmed> | |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 20:04, 5 October 2009
- Description: transcriptional negative regulator of the spore photoproduct lyase operon
| Gene name | splA |
| Synonyms | ykxI |
| Essential | no |
| Product | transcriptional regulator |
| Function | regulation of the splA-splB operon |
| MW, pI | 9 kDa, 4.419 |
| Gene length, protein length | 237 bp, 79 aa |
| Immediate neighbours | ptsI, splB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU13920
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P37955
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190]
[WorldCat.org]
[DOI]
(P p)
M Pedraza-Reyes, F Gutiérrez-Corona, W L Nicholson
Temporal regulation and forespore-specific expression of the spore photoproduct lyase gene by sigma-G RNA polymerase during Bacillus subtilis sporulation.
J Bacteriol: 1994, 176(13);3983-91
[PubMed:8021181]
[WorldCat.org]
[DOI]
(P p)
