Difference between revisions of "YcsA"
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=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''ycsA'' (according to [http://dbtbs.hgc.jp/COG/prom/ycsA.html DBTBS]) |
* '''[[Sigma factor]]:''' | * '''[[Sigma factor]]:''' | ||
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* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
Revision as of 18:48, 20 August 2009
- Description: malic enzyme
| Gene name | ycsA |
| Synonyms | |
| Essential | no |
| Product | D-malate dehydrogenase (NAD) |
| Function | malic enzyme, links TCA cycle to gluconeogenesis |
| MW, pI | 38 kDa, 5.108 |
| Gene length, protein length | 1062 bp, 354 aa |
| Immediate neighbours | mtlD, sipU |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU04000
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Tartrate + NAD+ = oxaloglycolate + NADH (according to Swiss-Prot)
- Protein family: isocitrate and isopropylmalate dehydrogenases family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P42958
- KEGG entry: [3]
- E.C. number: 1.1.1.93
Additional information
Expression and regulation
- Operon: ycsA (according to DBTBS)
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
