LipC

• Description: lipase implicated in spore germination
  
  

Gene name	lipC
Synonyms	ycsK
Essential	no
Product	lipase
Function	spore germination
MW, pI	23 kDa, 5.839
Gene length, protein length	639 bp, 213 aa
Immediate neighbours	kipR, yczI
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU04110

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: 'GDSL' lipolytic enzyme family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: spore wall (according to Swiss-Prot), mother cell PubMed

Database entries

• Structure:

• UniProt: P42969

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor: SigK PubMed

• Regulation: expressed four hours after onset of sporulation (GerE) PubMed

• Regulatory mechanism: GerE: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Atsushi Masayama, Ritsuko Kuwana, Hiromu Takamatsu, Hisashi Hemmi, Tohru Yoshimura, Kazuhito Watabe, Ryuichi Moriyama
A novel lipolytic enzyme, YcsK (LipC), located in the spore coat of Bacillus subtilis, is involved in spore germination.
J Bacteriol: 2007, 189(6);2369-75
[PubMed:17220230] [WorldCat.org] [DOI] (P p)