GutR

• Description: transcription activator of the gutB-gutP operon
  
  

Gene name	gutR
Synonyms
Essential	no
Product	transcription activator
Function	regulation of glucitol utilization
Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism
MW, pI	94 kDa, 6.113
Gene length, protein length	2487 bp, 829 aa
Immediate neighbours	ydjC, gutB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU06140

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P39143

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

K K Poon, J C Chu, S L Wong
Roles of glucitol in the GutR-mediated transcription activation process in Bacillus subtilis: glucitol induces GutR to change its conformation and to bind ATP.
J Biol Chem: 2001, 276(32);29819-25
[PubMed:11390381] [WorldCat.org] [DOI] (P p)

K K Poon, C L Chen, S L Wong
Roles of glucitol in the GutR-mediated transcription activation process in Bacillus subtilis: tight binding of GutR to tis binding site.
J Biol Chem: 2001, 276(13);9620-5
[PubMed:11118449] [WorldCat.org] [DOI] (P p)

R Ye, S N Rehemtulla, S L Wong
Glucitol induction in Bacillus subtilis is mediated by a regulatory factor, GutR.
J Bacteriol: 1994, 176(11);3321-7
[PubMed:8195087] [WorldCat.org] [DOI] (P p)

R Ye, S L Wong
Transcriptional regulation of the Bacillus subtilis glucitol dehydrogenase gene.
J Bacteriol: 1994, 176(11);3314-20
[PubMed:8195086] [WorldCat.org] [DOI] (P p)