LytB

• Description: modifier protein of major autolysin LytC
  
  

Gene name	lytB
Synonyms	cwbA
Essential	no
Product	modifier protein of major autolysin LytC
Function	autolysis
MW, pI	76 kDa, 9.835
Gene length, protein length	2115 bp, 705 aa
Immediate neighbours	lytC, lytA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU35630

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: Q02113

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: lytA-lytB-lytC

• Sigma factor: SigA, SigD

• Regulation:

• Regulatory mechanism: repressed by YvrHb PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

V Lazarevic, P Margot, B Soldo, D Karamata
Sequencing and analysis of the Bacillus subtilis lytRABC divergon: a regulatory unit encompassing the structural genes of the N-acetylmuramoyl-L-alanine amidase and its modifier.
J Gen Microbiol: 1992, 138(9);1949-61
[PubMed:1357079] [WorldCat.org] [DOI] (P p)

A Kuroda, J Sekiguchi
Characterization of the Bacillus subtilis CwbA protein which stimulates cell wall lytic amidases.
FEMS Microbiol Lett: 1992, 74(1);109-13
[PubMed:1355454] [WorldCat.org] [DOI] (P p)