Difference between revisions of "DegA"

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* '''Structure:'''
 
* '''Structure:'''
  
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P37947 P37947]
+
* '''UniProt:''' [http://www.uniprot.org/uniprot/P37947 P37947]
  
 
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU10840]
 
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU10840]

Revision as of 11:51, 20 July 2009

  • Description: transcriptional activator involved in the degradation of glutamine phosphoribosylpyrophosphate amidotransferase

Gene name degA
Synonyms
Essential no
Product transcriptional activator (LacI family)
Function unknown
MW, pI 36 kDa, 5.784
Gene length, protein length 1011 bp, 337 aa
Immediate neighbours yisR, yisS
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
DegA context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU10840

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information: the mRNA is very stable (half-life > 15 min) PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

G Hambraeus, C von Wachenfeldt, L Hederstedt
Genome-wide survey of mRNA half-lives in Bacillus subtilis identifies extremely stable mRNAs.
Mol Genet Genomics: 2003, 269(5);706-14
[PubMed:12884008] [WorldCat.org] [DOI] (P p)

L B Bussey, R L Switzer
The degA gene product accelerates degradation of Bacillus subtilis phosphoribosylpyrophosphate amidotransferase in Escherichia coli.
J Bacteriol: 1993, 175(19);6348-53
[PubMed:8407808] [WorldCat.org] [DOI] (P p)