Difference between revisions of "PbpA"

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|style="background:#ABCDEF;" align="center"| '''Product''' || penicillin-binding protein PBP 2A
 
|style="background:#ABCDEF;" align="center"| '''Product''' || penicillin-binding protein PBP 2A
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || spore outgrowth
+
|style="background:#ABCDEF;" align="center"|'''Function''' || formation of a rod-shaped peptidoglycan cell wall, spore outgrowth
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 79 kDa, 9.571   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 79 kDa, 9.571   
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=References=
 
=References=
  
<pubmed>9851991,9139922,,18957862, </pubmed>
+
<pubmed>9851991,9139922,12896990 ,18957862, </pubmed>

Revision as of 07:55, 13 July 2009

  • Description: penicillin-binding protein PBP 2A

Gene name pbpA
Synonyms yqgF
Essential no
Product penicillin-binding protein PBP 2A
Function formation of a rod-shaped peptidoglycan cell wall, spore outgrowth
MW, pI 79 kDa, 9.571
Gene length, protein length 2148 bp, 716 aa
Immediate neighbours pstS, yqgE
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PbpA context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU25000

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: extracellular (signal peptide) PubMed

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system: B. pertussis adenylate cyclase-based bacterial two hybrid system (BACTH), available in Jeff Errington lab
  • Antibody:

Labs working on this gene/protein

Jeff Errington, Newcastle University, UK homepage

Your additional remarks

References