Difference between revisions of "GlpQ"
(→Expression and regulation) |
|||
| Line 88: | Line 88: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''[[glpT]]-[[glpQ]]'' |
| − | * '''[[Sigma factor]]:''' | + | * '''[[Sigma factor]]:''' [[SigA]] |
* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** | + | ** repressed by glucose (6.2-fold) ([[CcpA]]) [http://www.ncbi.nlm.nih.gov/pubmed/12850135 PubMed] |
| + | ** induced by glycerol ([[GlpP]]) | ||
| + | ** induced by phosphate limitation ([[PhoP]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/10913081 PubMed] | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[CcpA]]: transcription repression | ||
| + | ** [[GlpP]]: transcriptional antitermination ''via'' a protein-dependent [[RNA switch]] | ||
** [[PhoP]]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/10913081 PubMed] | ** [[PhoP]]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/10913081 PubMed] | ||
| − | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
Revision as of 20:35, 6 July 2009
- Description: glycerolphosphate diester phosphodiesterase
| Gene name | glpQ |
| Synonyms | ybeD |
| Essential | no |
| Product | glycerolphosphate diester phosphodiesterase |
| Function | glycerol-3-phosphate utilization |
| MW, pI | 32 kDa, 9.263 |
| Gene length, protein length | 879 bp, 293 aa |
| Immediate neighbours | ybeC, glpT |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU02130
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: A glycerophosphodiester + H2O = an alcohol + sn-glycerol 3-phosphate (according to Swiss-Prot)
- Protein family: glycerophosphoryl diester phosphodiesterase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: extracellular (signal peptide) PubMed
Database entries
- Structure:
- Swiss prot entry: P37965
- KEGG entry: [3]
- E.C. number: 3.1.4.46
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- CcpA: transcription repression
- GlpP: transcriptional antitermination via a protein-dependent RNA switch
- PhoP: transcription activation PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
